Saffron Oil (Crocus sativus) Essential Oil 100% Pure Natural Undiluted Uncut Therapeutic Grade Oil 0.16 Fl.Oz to 33.81 Fl.Oz by Sheer Essence (Saffron Oil (Crocus sativus) Oil, 5ML (0.16 Fl.OZ))

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PubMed: Rapid determination of crocetin esters and picrocrocin from saffron spice (Crocus sativus L.) using UV-visible spectrophotometry for quality control. The saffron oil infused from the threads of saffron is one of the most important oils with benefits for health including skin and hair. This saffron oil made at home is a much sought-after and preferred recipe. Additionally, a 2018 animal study found that crocin improves atopic dermatitis in mice. The atopic dermatitis was caused by Dermatophagoides farinae (house mite) extract, which commonly causes the condition in humans. Supports wound healing

Nature In Bottle certify that Saffron Oil is compliant with the Senate Bill S4389B An Act to Amend the Environmental Conservation Law, in Relation to Prohibiting Household Cleansing Products, Cosmetic Products and Personal Care Products that Contain 1,4-Dioxane, which limits the trace concentration of 1,4-dioxane to 1 ppm. Verjee S, et al. (2017). Saffron flower extract promotes scratch wound closure of keratinocytes and enhances VEGF production. DOI:

PubMed: Protective effect of aqueous saffron extract (Crocus sativus L.) and crocin, its active constituent, on renal ischemia-reperfusion-induced oxidative damage in rats. Saffron, like many other herbs and plants, is rich in antioxidants. These substances help fight cell damage and may prevent cancer or other diseases. Research has also shown that the antioxidants in saffron may be healthy for your brain and nervous system.

PubMed: Saffron (Crocus sativus) aqueous extract and its constituent crocin reduces stress-induced anorexia in mice. One interesting recent clinical study was however published in 2015. The researchers looked at the effects of saffron on thirteen patients suffering from liver cancer while they were undergoing chemotherapy treatment. The patients were divided into two groups and either treated with saffron or given a placebo.

Based on the ISO 16128-1:2016 (Definitions for ingredients) and ISO 16128-2:2017 (Criteria for ingredients and products), Nature In Bottle can advise that Saffron Oil would have a Natural Origin Index of 1 and therefore, could be considered to come under the definition of a 'Natural Ingredient'. Saffron oil releases serotonin in the body and helps fight depression and anxiety. It also promotes good sleep and treats the condition of insomnia. Saffron oil is also known to reverse the symptoms of insomnia. [5] Weight Loss